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Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Amaral EP, et al. Among authors: salles em. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 24991816 Free PMC article.
P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria.
Salles ÉM, Menezes MN, Siqueira R, Borges da Silva H, Amaral EP, Castillo-Méndez SI, Cunha I, Cassado ADA, Vieira FS, Olivieri DN, Tadokoro CE, Alvarez JM, Coutinho-Silva R, D'Império-Lima MR. Salles ÉM, et al. PLoS Pathog. 2017 Aug 31;13(8):e1006595. doi: 10.1371/journal.ppat.1006595. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28859168 Free PMC article.